Filoviridae

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Filoviridae
Marburg virus
Marburg virus particles, ~100,000x magnification

Template:Taxobox begin placement virus Template:Taxobox group v entry

Order:Mononegavirales
Family:Filoviridae

|- style="text-align:center; background:violet;" !Genera |- | style="padding: 0 .5em;" | Marburgvirus
Ebolavirus |} Filoviruses are viruses belonging to the family Filoviridae, which is in the order Mononegavirales. Those viruses are single stranded negative sense RNA viruses that target primates. There are two genera, the Ebola viruses (Ebolavirus, with four species) [1] (http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/ebola.htm) and the Marburg virus (Marburgvirus).

These viruses cause viral hemorraghic fevers, characterized by massive bleeding from every orifice of the body. These diseases are shockingly lethal, with very high mortality rates and possibility of transfer. They are classified by the CDC as BSL4, or biosafety level 4. This means that they are among the most lethal and destructive viruses known to man.

The virions (viral particles) are characteristically shaped as long, cylindrical, filamentous particles which may be straight, curved, coiled, or found in a "6" or "U" shaped configuration. They are occasionally branched and the particles vary greatly in length but the diameter (about 80nm) is consistent.

They are produced by budding from an infected cell, and consist of the viral RNA strand and proteins encapsulated in a lipid membrane formed from the host cell's plasma membrane.


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